The Use of Chloranilic Acid for the Spectrophotometric Determination of Three Macrolides through Charge Transfer Complex
نویسندگان
چکیده
منابع مشابه
Spectrophotometric Determination of Astemizole and Loratadine Based on Charge-Transfer Complex Formation with Chloranilic Acid
A simple and sensitive spectrophotometric method for the assay of two antihistamines, astemizole and loratadine, is described. The determination was based on the formation of chargetransfer complexes between chloranilic acid as a p acceptor and the studied drugs as n-donors in acetonitrile solvent. The spectra, various experimental parameters, composition and formation constant of the complexes...
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The three antihistaminic drugs investigated are of diverse chemical types, and many chemical methods have been reported for their assay. Cyproheptadine hydrochloride (CPH) is a serotonin and a histamine antagonist with anticholinergic and sedative effects. It also blocks voltage sensitive calcium channels in pancreatic islet cells and smooth muscle. CPH is also used as an appetite stimulant to ...
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ژورنال
عنوان ژورنال: Medicinal chemistry
سال: 2013
ISSN: 2161-0444
DOI: 10.4172/2161-0444.1000146