The Use of Chloranilic Acid for the Spectrophotometric Determination of Three Macrolides through Charge Transfer Complex

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Spectrophotometric Determination of Astemizole and Loratadine Based on Charge-Transfer Complex Formation with Chloranilic Acid

A simple and sensitive spectrophotometric method for the assay of two antihistamines, astemizole and loratadine, is described. The determination was based on the formation of chargetransfer complexes between chloranilic acid as a p acceptor and the studied drugs as n-donors in acetonitrile solvent. The spectra, various experimental parameters, composition and formation constant of the complexes...

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ژورنال

عنوان ژورنال: Medicinal chemistry

سال: 2013

ISSN: 2161-0444

DOI: 10.4172/2161-0444.1000146